Article Text
Correspondence
Incidental freezing artefacts in sentinel lymph node biopsies masquerading as lymphangiography artefacts
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Sentinel lymph node (SLN) biopsy is a widely used staging procedure. As recently reviewed, possible problems with microscopic interpretation include false positive immunohistochemical staining and benign lesions mimicking metastasis.1 To my knowledge, no histological artefacts, especially no lymphangiography artefacts, have been attributed to this procedure. I recently encountered an artefact that at first glance seemed to be a lymphangiography artefact.
SLN biopsy is used in our hospital for the staging of breast cancer and was introduced in July 2001. The details of our procedure are as follows. The radioactive tracer is injected intracutaneously or subcutaneously in the affected quadrant of the breast 24 …