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- Published on: 14 November 2005
- Published on: 1 September 2005
- Published on: 14 November 2005Re: Dangers of Bouin's Fixation.Show More
Dear Editor
In a previous issue of this journal, we presented problems of using Bouin’s fixative for immunohistochemical and nuclear morphometric assays on prostatic biopsies(1). We agree with the important comment offered by Berney that Bouin’s fixative could increase the sensitivity for detection of high grade prostatic intraepithelial neoplasia (HGPIN) and prostate cancer. Furthermore, we agree that increa...
Conflict of Interest:
None declared. - Published on: 1 September 2005Dangers of Bouin's Fixation.Show More
Dear Editor,
I read with interest the paper by Ananthanarayanan et al.[1] on ‘Immunohistochemical assays in prostatic biopsies processed in Bouin’s fixative’. They rightly point out the problems encountered when trying to perform immunohistochemistry or other molecular techniques on Bouin’s fixed biopsies.
However, there are other and more fundamental problems with Bouin’s fixative for prostatic tissue t...
Conflict of Interest:
None declared.