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J Clin Pathol 59:1029-1038 doi:10.1136/jcp.2005.035337
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Diagnosis and grading of dysplasia in Barrett’s oesophagus

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  Figure 4
Figure 4

 High-power view of high-grade dysplasia with intramucosal adenocarcinoma. The intramucosal adenocarcinoma is characterised by a proliferation of small irregular glands with markedly atypical nuclei infiltrating the lamina propria in a haphazard fashion that cannot be explained on the basis of involvement of pre-existing crypts.

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