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Crohn’s disease with inflammatory splenic granuloma
  1. J D Coyne
  1. Correspondence to:
 Department of Pathology
 Wythenshawe Hospital, Manchester M23 9LT, UK; johnnycoyne{at}doctors.org.uk

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The sites of extragastrointestinal granuloma formation in Crohn’s disease are numerous.1 As the association of the spleen has been recorded on only one previous occasion,2 I wish to highlight this occurrence and to draw attention to a possible association with aseptic abscess formation.

A 34-year-old man, with a history of rectal bleeding, abdominal pain and weight loss, on undergoing sigmoidscopy, was found to have mucosal congestion, extensive erythema with granularity, patchy mucopurulent exudates, multiple small ulcers and a patchy cobblestone mucosa affecting the sigmoid colon, but with rectal sparing. Microscopic examination showed mixed acute and chronic …

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