Figure 5
PCR with DNA extracted from bone marrow trephine (BMT) specimens. Lanes 1 and 4, a BMT specimen with no evidence of neoplastic disease. Lanes 2 and 5, a BMT specimen heavily affected by chronic lymphocytic leukaemia. Lanes 3 and 6, water control. Lanes 1–3, PCR analysis with primers for β-actin gene. Lanes 4–6, PCR analysis with FR3 and JH primers for identification of immunoglobulin heavy chain gene rearrangement. M, DNA marker.
