This review examines research findings in patients with myalgic encephalomyelitis in light of the current debate about this chronic multiple-symptom, multiorgan, multisystem illness and the conflicting views in medicine. These issues cannot be separated from the political opinions and assertions that conflict with science and medicine, and will be part of this review as they have enormous consequences for scientific and medical research, patients, clinicians, carers and policy makers.
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↵i This was an initiative of the Norfolk and East Anglia ME Association. Copies are available at cost from
↵ii This paper builds on the Peckerman paper, and using tests to evaluate ATP synthesis, translocation and utilisation provides a coherent basis for treatment with ribose, l-carnitine, CoQ 10, niacinamide and magnesium
Competing interests: None.
My thanks to Margaret Williams and Horace Reid for their help with the preparation of this document.
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