This article has a correction

Please see: J Clin Pathol 2008;61:1072

J Clin Pathol 60:466-471 doi:10.1136/jcp.2006.042408
  • Review

Myalgic encephalomyelitis: a review with emphasis on key findings in biomedical research

  1. M Hooper
  1. Correspondence to:
 M Hooper
 School of Health, Natural and Social Sciences, Fleming Building, University of Sunderland, Sunderland, SR1 3SD UK; malcolm.hooper{at}
  • Accepted 31 July 2006
  • Published Online First 25 August 2006


This review examines research findings in patients with myalgic encephalomyelitis in light of the current debate about this chronic multiple-symptom, multiorgan, multisystem illness and the conflicting views in medicine. These issues cannot be separated from the political opinions and assertions that conflict with science and medicine, and will be part of this review as they have enormous consequences for scientific and medical research, patients, clinicians, carers and policy makers.


  • i This was an initiative of the Norfolk and East Anglia ME Association. Copies are available at cost from Jeff{at}

  • ii This paper builds on the Peckerman paper, and using tests to evaluate ATP synthesis, translocation and utilisation provides a coherent basis for treatment with ribose, l-carnitine, CoQ 10, niacinamide and magnesium

  • Competing interests: None.

  • My thanks to Margaret Williams and Horace Reid for their help with the preparation of this document.

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