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Snippets in surgical pathology
  1. Kumarasen Cooper,
  2. Runjan Chetty
  1. kum.cooper@vtmednet.org
  2. runjan.chetty@uhn.on.ca

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This section will feature synopses of pertinent practical publications that appear in Pathology journals in the respective sub-specialties. The summaries are mere guidelines and personal opinions of the two authors. The articles selected are diverse but occasionally reflect the authors’ bias and are from the more widely read pathology journals. It is not intended to be an assiduous search of every publication in every Pathology journal, but more of a general indication of some of the monthly highlights through the eyes of the authors.

Hopefully, these snippets will provide the reader with enough to glean some facts and tips, as well as encourage them to read the entire article if necessary.

JOURNAL OF CLINICAL PATHOLOGY, JULY 2008

Oertel YC. Fine needle aspiration of the thyroid: a pathologist’s perspective. J Clin Pathol 2008;61:785–6.

An excellent personal insight of FNA of the thyroid based on 30 years of experience. Some nice pearls of wisdom for dabblers and full time exponents of cytopathology.

Volante M, Buttigliero C, Greco E, et al. Pathological and molecular features of adrenocortical carcinoma: an update. J Clin Pathol 2008;61:787–93.

An update on the pathological and molecular features of adrenocortical carcinoma, especially with respect to the Weiss criteria (which still appear to be superior to the molecular data). The authors approach the Weiss criteria thus:

  • three structural features (dark cytoplasm, diffuse architecture, necrosis)

  • three cytological features (atypia, mitoses, atypical mitoses)

  • three patterns of invasion (sinusoidal, veins, capsule).

While some of the criteria are simple to apply, others are subjective, such as: assessing a diffuse architecture or even being definitive about sinusoidal, venous or capsular invasion. Genetic or epigenetic alterations of some molecules, in particular p53 and IGF-2 may have prognostic and therapeutic applications.

Soor GS, Chakrabarti MO, Abraham JR, et al. Aortic stent grafts. J Clin Pathol 2008;61 …

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