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Prostatic involvement by nasal NK/T cell lymphoma forming lymphoepithelial lesions
  1. S-S Chuang1,
  2. S-T Chang2,
  3. Y-H Lee3,
  4. K-C Chang4
  1. 1
    Department of Pathology, Chi-Mei Medical Center, Tainan, and Taipei Medical University, Taipei, Taiwan
  2. 2
    Department of Pathology, Chi-Mei Medical Center, Tainan, Taiwan
  3. 3
    Department of Urology, Chi-Mei Medical Center, Tainan, Taiwan
  4. 4
    Department of Pathology, School of Medicine, National Cheng Kung University, Tainan, Taiwan
  1. Dr Shih-Sung Chuang, Department of Pathology, Chi-Mei Medical Center, 901 Chung-Hwa Road, Yung-Kang City, Tainan County, Taiwan 710; cmh5301{at}mail.chimei.org.tw

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Isaacson and Wright first introduced the concept of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) in those gastrointestinal low-grade B-cell lymphomas recapitulating the features of Peyer’s patch or MALT.1 Lymphoepithelial lesion (LEL) is a characteristic feature of MALT lymphoma.2 It is formed by invasion of individual crypts by aggregates of centrocyte-like (CCL) lymphocytes, which eventually leads to disintegration of the crypt epithelium.2 Extranodal NK/T-cell lymphoma of the nasal type is an aggressive lymphoma with frequent angioinvasion and tumour necrosis. To our knowledge, LEL has never been described in either NK- or T-cell lymphomas. We present a unique case of nasal NK/T-cell lymphoma involving the prostate in which LEL was prominent.

A 59-year-old Taiwanese male presented with acute urinary retention. He had had a stuffy nose and dysuria with urinary frequency for the past 3 months and …

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