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Although a wide spectrum of AIDS-related cholangiopathy has been reported periodically, malignant tumours, commonly seen in patients with AIDS, are very rare in the gallbladder, with only handful of reports in the literature: Kaposi’s sarcoma, and malignant lymphoma.1 2 We describe the first case of gallbladder adenocarcinoma in a patient with AIDS.
A 36-year-old man, HIV seropositive at 24, without familial history of gallbladder carcinoma, was hospitalised with right upper quadrant abdominal pain. He had chronic liver disease, hepatitis B virus-related, but no previous diagnosis of an HIV-related opportunistic infection. He was on highly active antiretroviral therapy (HAART); 2 years previously he had developed intestinal malignant non-Hodgkin lymphoma, treated by surgery and chemotherapy. The CD4+ lymphocyte count was 30/mm …