Journal of Clinical Pathology, April 2009

Bevilacqua G. Stromal tumours: which diagnostic approach? J Clin Pathol 2009;62:289.

This commentary reiterates the role of alk rearrangements in up to 70% of inflammatory myofibroblastic tumours (vs pseudosarcomatous myofibroblastic proliferations). These authors emphasise the role of FISH to accomplish this distinction to be a “modern updated pathologist.”

Tong LCB, Kamil ZS, Al Habeeb A, et al. Non-melanocytic mimics of melanoma, part II. J Clin Pathol 2009;62:290–307.

This is the second part of a two-part extravaganza on lesions that mimic melanoma. In this offering the authors concentrate on all the intradermal melanoma look-alikes. This is a detailed, comprehensive expose with brilliant tables. Although the illustrations are in black and white, this does not detract from the superb quality of this “My Approach” contribution. Well worth a read and photocopying the tables.

Human Pathology, April 2009

Lefkowitch JH. Recent developments in liver pathology. Hum Pathol 2009;40:445–55.

Nice comprehensive overview of liver pathology that is worth reading. A snippet is that the famous Mallory body has gained another name and is now called the Mallory–Denk body.

Higgins JP, McKenney JK, Brooks JD, et al. Recommendations for the reporting of surgically resected specimens of renal cell carcinoma: The Association of Directors of Anatomic and Surgical Pathology. Hum Pathol 2009;40:456–63.

A reporting checklist that provides all the information, especially the grading and staging, on renal cell carcinoma.

Lotan TL, Epstein JI. Gleason grading of prostatic adenocarcinoma with glomeruloid features on needle biopsy. Hum Pathol 2009;40:471–7.

Prostate carcinoma with glomeruloid features (dilated glands with intraluminal cribriform structures) are associated with concurrent Gleason grade 4 or higher, justifying that this pattern is best regarded as Gleason grade 4. It has been proposed that all cribriform patterns be regarded as Gleason grade 4.

Nazeer T, Kee KH, Ro JY, …