Table 1 CIOMS consensus criteria for terminology in drug-induced liver injury
| Terminology | Criteria |
| Hepatocellular injury | Isolated increase in ALT >twice normal, or ALT/ALP ⩾5 |
| Cholestatic injury | Isolated increase in ALP >twice normal, or ALT/ALP ⩽2 |
| Mixed injury | ALT and ALP are increased, and 2<ALT/ALP<5 |
| Acute injury | Above changes present for <3 months |
| Chronic injury | Above changes present for >3 months |
| Chronic liver disease | This term is used only after histological confirmation |
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ALP, alkaline phosphatase; ALT, alanine aminotransferase; CIOMS, Council for International Organizations of Medical Sciences.
