J Clin Pathol 62:584-592 doi:10.1136/jcp.2009.064311
  • Review

Cardiac pathology of systemic lupus erythematosus

  1. D Jain,
  2. M K Halushka
  1. Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
  1. Dr M K Halushka, Ross Building, RM 632L, 720 Rutland Avenue, Baltimore, MD 21205, USA; mhalush1{at}
  • Accepted 19 February 2009


Systemic lupus erythematosus is a common chronic autoimmune disorder causing injury to many organ systems. Cardiac complications of lupus affect most parts of the heart. These include pericarditis, myocarditis, endocarditis and coronary artery disease. While many histopathological findings in lupus-related cardiac diseases are non-specific, there are a few important findings which pathologists should be aware of. This review provides pathological descriptions of these entities.


  • Competing interests: None.