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- biological sciences
- cancer genetics
- cancer stem cells
- chronic myeloid
Mast cell sarcoma is an extremely rare mast cell proliferative disorder characterised by localised tumour, destructive growth and poor prognosis. Here we describe a case of mast cell sarcoma arising in the small intestine. To the best of our knowledge, so far only four cases have been reported in literature, presenting in the larynx, ascending colon, cerebrum and tibia.1–5
An elderly man presented with a 1.5-month history of abdominal pain. On examination, there was no lymphadenopathy or hepatosplenomegaly. Peripheral blood counts were normal except for mild anaemia. Serum lactate dehydrogenase was normal. CT abdomen showed a circumferential thickening of the wall of the ileum, with dilatation of bowel loops and a few enlarged mesenteric lymph nodes.
The patient underwent ileal resection and anastomosis. Gross examination revealed a segment of the small intestine measuring 15 cm in length, 4 and 8 cm in circumference at either resection margin. The external surface showed a constriction about 3 cm in length. The lumen showed an annular constrictive …