Snippets in surgical pathology
This section features synopses of pertinent practical publications that appear in Pathology journals in the respective sub-specialties. The summaries are mere guidelines and personal opinions of the two authors. The articles selected are diverse but occasionally reflect the authors' bias and are from the more widely read pathology journals. It is not intended to be an assiduous search of every publication in every Pathology journal, but more of a general indication of some of the monthly highlights through the eyes of the authors.
Hopefully, these snippets will provide the reader with enough to glean some facts and tips, as well as encourage them to read the entire article if necessary.
Journal of Clinical Pathology
There are five excellent articles on transplant-related pathology from page 12 to 74. These are of great value to pathologists encountering these sorts of biopsies occasionally rather than as a matter of routine.
Mahendra G, Kliskey K, Athanasou NA. Immunophenotypic distinction between pigmented villonodular synovitis and haemosiderotic synovitis. J Clin Pathol 2010;63:75–8.
The distinction between pigmented villonodular synovitis (PVNS) and hemosiderotic synovitis is critical for management. While the former is now considered to be neoplastic (with the potential to recur), the latter is a reactive phenomenon to hemarthrosis. MIB-1 expression is increased in PVNS and the mono/multinucleated cells express CD51.
American Journal of Surgical Pathology
Djordjevic B, Malpica A. Lymph node involvement in ovarian serous tumors of low malignant potential: a clinicopathologic study of thirty-six cases. Am J Surg Pathol 2010;34:1–9.
The controversy regarding lymph node involvement in borderline ovarian serous tumours seems closer to resolution, with this study demonstrating that lymph node involvement is not an independent predictor of disease-free survival, but is associated with a higher rate of implants—both invasive and non-invasive. Nevertheless, lymph node sampling in all borderline ovarian serous tumours is essential since lymph node …