Article Text

PDF
Gains of chromosomes 7 and 17 in tubulocystic carcinoma of kidney: two cases with fluorescence in situ hybridisation analysis
  1. Ni Chen,
  2. Ling Nie,
  3. Jing Gong,
  4. Xueqin Chen,
  5. Miao Xu,
  6. Min Chen,
  7. Qiao Zhou
  1. Department of Pathology and Laboratory of Pathology, State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China
  1. Correspondence to Dr Qiao Zhou, Department of Pathology, West China Hospital, West China Medical School, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, Sichuan 610041, China; 64548122{at}qq.com

Abstract

Tubulocystic carcinoma (TCC) is a very rare renal tumour with unique gross and microscopic features, alternatively considered as low-grade collecting duct carcinoma. Recent studies favoured distinction of TCC from collecting duct carcinoma, and some cases of TCC synchronously coexisting with other renal cell tumour subtypes were described. We report here two new cases of pure (case 1) or mixed (case 2) TCC with fluorescence in situ hybridisation (FISH) analysis, which showed gains of chromosomes 7 and 17 in the pure TCC of case 1, as well as in the TCC and the papillary renal cell carcinoma (PRCC) components in case 2. These data may further support the notion that TCC is more closely related to PRCC.

  • RENAL CANCER
  • FISH
  • UROPATHOLOGY

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.