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Isolated gastric crystal-storing histiocytosis: a rare marker of occult lymphoproliferative disorders
  1. Arjun Vaid1,
  2. Kari D Caradine2,
  3. Keith K Lai2,
  4. Rayburn Rego1
  1. 1Department of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
  2. 2Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
  1. Correspondence to Dr Arjun Vaid, Department of Gastroenterology and Hepatology, University of Arkansas for Medical Sciences, 4301 West Markham, Mail Slot 567, Shorey Building, Room S8/68, Little Rock, AR 72205, USA; arjunvaid{at}gmail.com

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Rare incidental endoscopic findings may have grave implications requiring a high index of suspicion with a low threshold for histopathological examination. We present a case of just such an incidental gastric lesion, which on histopathological analysis was determined to be Crystal-Storing Histiocytosis (CSH), a rare manifestation of lymphoproliferative disorders.

An elderly patient presented for an upper gastrointestinal endoscopy with longstanding symptoms suggestive of gastroesophageal acid reflux despite proton pump inhibitor use. The upper endoscopy reported a normal oesophagus and duodenum. However, a questionable submucosal lesion was noted in the antrum. This resulted in a referral to our centre for an endoscopic ultrasound (EUS). While performing the EUS, a 2 cm whitish patch was incidentally noted on the greater curvature of the …

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