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Inductively coupled plasma mass spectrometry is now the method of choice in routine clinical biochemistry practice for measuring a wide variety of trace elements.1 It allows accurate and precise analysis of trace elements that are often found at low concentration. Many trace elements have essential biological functions. Depletion of these may cause deficiency syndromes while excessive accumulation of certain elements may cause toxicity.
Trace elements are ubiquitous and contamination is a constant threat that can compromise the integrity of results.1 ,2 There are multiple potential sources of contamination, including sample containers, glassware and plastics used during analysis, reagents and physical aspects of the instrumentation itself.
Iodine is an essential trace element and is an integral component of thyroid hormones that are essential for growth and development. Deficiency of iodine is …