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Sebaceous hyperplasia of the vulva: a clinicopathological case report with a review of the literature
  1. Wael Ismail Al-Daraji (waldaraji{at}aol.com)
  1. Darent Valley Hospital, United Kingdom
    1. Brian E Wagner
    1. Sheffield University Teaching Hospitals, United Kingdom
      1. Andrew McDonagh
      1. Sheffield University Teaching Hospitals, United Kingdom
        1. Rokiah BM Ali
        1. Sheffield University Teaching Hospitals, United Kingdom

          Abstract

          Sebaceous hyperplasia consists of multiple asymptomatic small yellow papules with a central depression occurring most commonly on the forehead and cheeks, but occasionally affecting the areola, chest or genital skin. Sebaceous hyperplasia of the vulva is exceedingly rare, and only 3 cases have been reported in the literature, so far. The addition of this case to the world literature offers new clinicopathological data useful for better defining this entity on the vulva. It is important to differentiate sebaceous hyperplasia from Fordyce’s granules as the latter are normally present on the whole surface on the labia minora and are usually missed histologically. We report a unique case of sebaceous hyperplasia of the vulva as evident by morphologic findings, electron microscopy studies and immunophenotype.

          • Electron microscopy
          • Fordyce's granules
          • Immunohistochemistry,
          • Sebaceous hyperplasia of the vulva
          • melanotic macule

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