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Fatal case of sepsis caused by a non-haemolytic strain of Streptococcus pyogenes
  1. David P. J. Turner (david.turner{at}
  1. Nottingham University Hospitals NHS Trust, United Kingdom
    1. Sarah L. Gunn
    1. Nottingham University Hospitals NHS Trust, United Kingdom


      The beta-haemolytic phenotype of Streptococcus pyogenes on blood media, which is due to the liberation of streptolysin S, is critical to the recognition of this pathogen in the diagnostic laboratory. A case is reported of the isolation of a non-haemolytic variant of S pyogenes from a blood culture that was taken from a patient who died of sepsis. Non-haemolytic isolates of S pyogenes are uncommon, very rarely associated with bacteraemia or sepsis, and may be difficult to recognise especially if isolated from non-sterile sites.

      • Non-haemolytic
      • Sepsis
      • Streptococcus pyogenes

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