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A simple automated device for children's renal biopsy: advantage in obtaining more tissue
  1. Jian Chen1,
  2. Zihua Yu2,
  3. Juan Huang,
  4. Huakun Lin1,
  5. Xingxiang Gao1,
  6. Feng Zheng1
  1. 1Department of Nephrology, Dong Fang Hospital, Medical College of Xiamen University, Fuzhou, Fujian, China
  2. 2Department of Pediatrics, Dong Fang Hospital, Medical College of Xiamen University, Fuzhou, Fujian, China
  1. Correspondence to Feng Zheng, Department of Nephrology, Dong Fang Hospital, Medical College of Xiamen University, 156 Xi Er Huan Bei Road, Fuzhou, Fujian 350025, China; fzheng63{at}hotmail.com

Abstract

Sufficient tissue yield is essential for renal biopsy. We have developed a simple automated renal biopsy device (Chen device) that constantly obtains more tissue. Since the Bard device is extensively used around the world, we compared our device with the Bard device. Pediatric patients were biopsied with either the Chen (n=247) or Bard (n=200) devices. No major complications were encountered and the incidence of minor complications was comparable between two devices. However, the average length of tissue obtained by the Chen device per biopsy (1.78±0.73 cm) was significantly longer than that obtained by the Bard device (1.23±0.45 cm). Accordingly, 61.94% of biopsies with the Chen device had 20 or more glomeruli, whereas only 18% of biopsies with the Bard device had this number (p<0.001). Thus, the Chen device has the advantage of obtaining more renal tissue per biopsy while being equally efficient and safe as the Bard device.

  • Antibiotics
  • asthma
  • autoantibody
  • biopsy device
  • children
  • colorectal cancer
  • gall bladder
  • molecular pathology
  • morphometry
  • oncogenes
  • paediatric pathology
  • pancreas
  • P53
  • quality control
  • renal biopsy
  • renal nephrology

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.

  • Ethics approval The study and the procedures were approved by the Internal Review Board of Dong Fang Hospital.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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