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Authors' response - The prognostic benefits of routine staining with elastica to increase detection of venous invasion in colorectal cancer specimens
  1. David E Messenger1,2,
  2. David K Driman3,4,
  3. Richard Kirsch5,6
  1. 1Zane Cohen Clinical Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada
  2. 2Division of General Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada
  3. 3Department of Pathology, London Health Sciences Centre, London, Ontario, Canada
  4. 4Department of Pathology, University of Western Ontario, London, Ontario, Canada
  5. 5Department of Pathology, University of Toronto, Toronto, Canada
  6. 6Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada
  1. Correspondence to Dr Richard Kirsch, Assistant Professor, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada; rkirsch{at}mtsinai.on.ca

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The recent study by Roxburgh et al1 is the first to demonstrate that the routine use of an elastin stain to detect venous invasion (VI) in colorectal cancer specimens is a better predictor of long-term outcome than a standard H&E stain alone. It is interesting to note that the threefold increase in the detection of VI observed by these authors following the introduction of routine elastin staining was applicable to a group of general pathologists. Both in North America and the UK, the provision of colorectal cancer services is not centralised and institutions that offer exclusive reporting of colorectal cancer specimens by subspecialist gastrointestinal (GI) pathologists are in the minority. Clearly, the …

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