Statistics from Altmetric.com
A 45-year-old woman is found, on family history screening, to have calcification within the upper outer quadrant of her right breast. A diagnostic mammotome biopsy was performed. Review the interactive digital slide and consider your diagnosis and appropriate management.
What is your diagnosis?
Flat epithelial atypia with psammomatous calcification
Liesegang rings with lactational changes
Spheroid type amyloid
Histologically, there are focal collections of dilated ducts and microcysts lined by vacuolated epithelium showing lactational change. Many rounded concentric calcifications of various sizes are seen within the ductal lumina. These show characteristic appearances of Liesegang rings. In some ducts, the rings surround amorphous material with histologically identifiable calcific deposits. A mild chronic inflammatory infiltrate is seen in-between ducts.
Liesegang rings are spherical, ring-like …