Clinical question A 45-year-old woman is found, on family history screening, to have calcification within the upper outer quadrant of her right breast. A diagnostic mammotome biopsy was performed. Review the interactive digital slide and consider your diagnosis and appropriate management.

What is your diagnosis?

1. Collagenous spherulosis

2. Flat epithelial atypia with psammomatous calcification

3. Liesegang rings with lactational changes

4. Parasitic infection

5. Spheroid type amyloid