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Neural and neurogenic tumours of the gastroenteropancreaticobiliary tract
  1. Aoife J McCarthy1,
  2. Dipti M Karamchandani2,
  3. Runjan Chetty1
  1. 1 Department of Pathology, Laboratory Medicine Program, University Health Network and University of Toronto, Toronto, Ontario, Canada
  2. 2 Department of Pathology, Division of Anatomic Pathology, Penn State Health Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA
  1. Correspondence to Dr Aoife J McCarthy, Department of Pathology, Laboratory Medicine Program, University Health Network and University of Toronto, Toronto, ON M5G 2C4, Canada. ; aoife.mccarthy{at}uhn.ca

Abstract

Neural lesions occur uncommonly in the gastroenteropancreaticobiliary tract. However, due to the growing number of screening colonoscopy procedures, polypoid neural lesions of the colon are being recognised increasingly and range from benign tumours to high-grade malignant neoplasms. Morphological variability of neural tumours can be wide, although some entities share pathological features, and, as such, these lesions can be diagnostically challenging. We review the spectrum of pathology of neural tumours in the gastroenteropancreaticobiliary tract, with the goal of providing a practical approach for practising surgical pathologists.

  • Gastrointestinal tract
  • nerve sheath tumours
  • neural lesions
  • spindle cell neoplasms

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Footnotes

  • Handling editor Tahir S Pillay.

  • Contributors All authors contributed equally.

  • Funding This research received no specific grant from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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