Chest
Volume 124, Issue 1, July 2003, Pages 367-371
Opinions/HypothesesWhat Is Sarcoidosis?
Section snippets
Conclusions
The operational definition of sarcoidosis advanced by Scadding and Mitchell4 circumvents ambiguities that arise from the currently accepted descriptive definition. Subsumed within this definition is the concept that sarcoidosis is, most likely, etiologically heterogeneous.
It appears likely that the granulomas characterizing sarcoidosis are a response to an antecedent, inefficient, and uncharacterized abnormality in cell-mediated immunity. Its corollary—that suppression of this response with CST
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Dr. Reich is in private practice in Portland, OR
Copyright © 2003 The American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.