Chest
Volume 124, Issue 1, July 2003, Pages 367-371
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Opinions/Hypotheses
What Is Sarcoidosis?

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Conclusions

The operational definition of sarcoidosis advanced by Scadding and Mitchell4 circumvents ambiguities that arise from the currently accepted descriptive definition. Subsumed within this definition is the concept that sarcoidosis is, most likely, etiologically heterogeneous.

It appears likely that the granulomas characterizing sarcoidosis are a response to an antecedent, inefficient, and uncharacterized abnormality in cell-mediated immunity. Its corollary—that suppression of this response with CST

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  • Cited by (0)

    1

    Dr. Reich is in private practice in Portland, OR

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