Abstract
Microsatellite instability (MSI) induces carcinoma through the alteration of target genes; TGF-beta RII, BAX, IGFIIR, hMSH3, and hMSH6. The grade of M
MeSH terms
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Adult
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Aged
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Aged, 80 and over
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Amino Acid Sequence
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Base Pair Mismatch / genetics*
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Base Sequence
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Carcinoma / genetics*
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Carcinoma / pathology
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Colorectal Neoplasms / genetics*
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Colorectal Neoplasms / pathology
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DNA Repair / genetics*
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DNA, Neoplasm / genetics*
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DNA-Binding Proteins / genetics
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Female
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Frameshift Mutation*
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Humans
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Male
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Microsatellite Repeats / genetics*
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Middle Aged
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Multidrug Resistance-Associated Proteins*
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MutS Homolog 3 Protein
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Polymerase Chain Reaction
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Protein Serine-Threonine Kinases
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Proto-Oncogene Proteins / genetics
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Proto-Oncogene Proteins c-bcl-2*
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Receptor, IGF Type 2 / genetics
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Receptor, Transforming Growth Factor-beta Type II
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Receptors, Transforming Growth Factor beta / genetics
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Transforming Growth Factor beta / genetics*
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bcl-2-Associated X Protein
Substances
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BAX protein, human
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DNA, Neoplasm
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DNA-Binding Proteins
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G-T mismatch-binding protein
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MSH3 protein, human
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Multidrug Resistance-Associated Proteins
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MutS Homolog 3 Protein
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Proto-Oncogene Proteins
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Proto-Oncogene Proteins c-bcl-2
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Receptor, IGF Type 2
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Receptors, Transforming Growth Factor beta
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Transforming Growth Factor beta
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bcl-2-Associated X Protein
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Protein Serine-Threonine Kinases
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Receptor, Transforming Growth Factor-beta Type II
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multidrug resistance-associated protein 1