Primary pleuro-pulmonary malignant germ cell tumours

J Postgrad Med. 2002 Jan-Mar;48(1):29-31.

Abstract

Lungs and pleura are rare sites for malignant germ-cell tumours. Two cases, pure yolk-sac tumour and yolk sac-sac tumour/embryonal carcinoma are described in young males who presented with rapid progression of respiratory symptoms. The malignant mixed germ cell tumour occurred in the right lung, while the yolk-sac tumour had a pseudomesotheliomatous growth pattern suggesting a pleural origin. Alpha-foetoprotein was immunohistochemically demonstrated in both.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Adult
  • Endodermal Sinus Tumor / pathology*
  • Fatal Outcome
  • Humans
  • Lung Neoplasms / pathology*
  • Male
  • Pleural Neoplasms / pathology*
  • alpha-Fetoproteins / analysis

Substances

  • alpha-Fetoproteins