Myelofibrosis and angiodysplasia of the colon: another manifestation of portal hypertension and massive splenomegaly?

T Biss; P Hamilton

doi:10.1136/jcp.2003.015479

Myelofibrosis and angiodysplasia of the colon: another manifestation of portal hypertension and massive splenomegaly?

J Clin Pathol. 2004 Sep;57(9):999-1000. doi: 10.1136/jcp.2003.015479.

Authors

T Biss¹, P Hamilton

Affiliation

¹ Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK. tbiss@dsl.pipex.com

Abstract

Bleeding owing to portal hypertensive colopathy, a form of large bowel angiodysplasia, as a cause of increased blood transfusion requirement is described in a 74 year old man with idiopathic myelofibrosis. The proposed mechanism and the potential therapeutic options for this rare complication of myelofibrosis are discussed.

Publication types

Case Reports
Review

MeSH terms

Aged
Angiodysplasia / complications*
Angiodysplasia / pathology
Angiodysplasia / therapy
Blood Transfusion
Colon
Colonic Diseases / complications*
Colonic Diseases / pathology
Colonic Diseases / therapy
Fatal Outcome
Gastrointestinal Hemorrhage / etiology
Gastrointestinal Hemorrhage / pathology
Gastrointestinal Hemorrhage / therapy
Humans
Hypertension, Portal / complications*
Hypertension, Portal / pathology
Hypertension, Portal / therapy
Intestinal Mucosa / blood supply
Intestinal Mucosa / pathology
Male
Primary Myelofibrosis / complications*
Primary Myelofibrosis / pathology
Primary Myelofibrosis / therapy
Splenomegaly / complications*
Splenomegaly / pathology
Splenomegaly / therapy