Arrhythmogenic right ventricular dysplasia: from genetics to treatment

Anadolu Kardiyol Derg. 2009 Dec:9 Suppl 2:24-31.

Abstract

Arrhythmogenic right ventricular dysplasia (ARVD), also known as arrhythmogenic right ventricular cardiomyopathy, is a genetic cause for sudden cardiac arrest. In ARVD, there is progressive replacement of normal myocytes, with fat and fibrous tissue, predominantly in the right ventricle that predisposes the individual to arrhythmias. Patients who are identified with this condition are risk stratified; those at high risk are recommended to have implanted cardioverter defibrillators.

MeSH terms

  • Arrhythmias, Cardiac / etiology
  • Arrhythmias, Cardiac / prevention & control
  • Arrhythmogenic Right Ventricular Dysplasia / complications*
  • Arrhythmogenic Right Ventricular Dysplasia / genetics*
  • Arrhythmogenic Right Ventricular Dysplasia / therapy
  • Death, Sudden, Cardiac / etiology*
  • Death, Sudden, Cardiac / prevention & control
  • Defibrillators, Implantable*
  • Genetic Predisposition to Disease
  • Genetic Testing
  • Heart Ventricles / pathology*
  • Humans
  • Myocardium / pathology
  • Prognosis
  • Risk Assessment