Current issues in diagnostic breast pathology

J Clin Pathol. 2012 Sep;65(9):771-85. doi: 10.1136/jclinpath-2012-200733. Epub 2012 Jul 19.

Abstract

On behalf of the NHS Breast Screening Programme Pathology Coordinating Group we present recommendations for terminology and diagnostic criteria for a number of key areas of practice in breast pathology where terminology can be confusing and where accurate communication will ensure appropriate clinical management. These recommendations cover columnar cell lesions and the spectrum of changes that can be seen in these epithelial proliferations, lobular neoplasia, micrometastases and isolated tumour cells in axillary lymph nodes, the use of basal/myoepithelial markers in diagnostic practice and oestrogen receptor testing in ductal carcinoma in situ.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Biomarkers, Tumor / genetics
  • Biopsy
  • Breast / chemistry
  • Breast / pathology*
  • Breast Diseases / classification
  • Breast Diseases / genetics
  • Breast Diseases / metabolism
  • Breast Diseases / pathology*
  • Breast Neoplasms / chemistry
  • Breast Neoplasms / classification
  • Breast Neoplasms / genetics
  • Breast Neoplasms / pathology*
  • Clinical Laboratory Techniques* / classification
  • Clinical Laboratory Techniques* / standards
  • Diagnosis, Differential
  • Epithelial Cells / pathology
  • Female
  • Genetic Markers
  • Humans
  • Immunohistochemistry
  • Mammary Glands, Human / pathology
  • Molecular Diagnostic Techniques
  • Practice Guidelines as Topic
  • Predictive Value of Tests
  • Prognosis
  • Terminology as Topic

Substances

  • Biomarkers, Tumor
  • Genetic Markers