Abstract
A newly recognized type of dimorphic carcinoma of breast, distinct from adenoid cystic carcinoma, is described. It is characterized by a predominantly solid, clear cell myoepithelial proliferation, with centrally situated glandular lumina lined by apocrine cells. All cases arose in association with a distinctive type of atypical apocrine adenosis which has to be distinguished from microglandular adenosis and from tubular carcinoma. The biological behaviour of the tumour remains to be ascertained on the basis of longer follow-up, but it appears to have only limited malignant potential.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Actins / analysis
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Aged
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Apolipoproteins D
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Apolipoproteins*
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Breast Neoplasms / analysis
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Breast Neoplasms / complications
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Breast Neoplasms / ultrastructure*
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Carrier Proteins*
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Female
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Fibrocystic Breast Disease / complications
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Fibrocystic Breast Disease / pathology*
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Glycoproteins*
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Humans
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Immunohistochemistry
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Membrane Glycoproteins / analysis
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Membrane Transport Proteins*
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Microscopy, Electron
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Middle Aged
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Mucin-1
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Myoepithelioma / pathology*
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Myoepithelioma / ultrastructure
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Neoplasm Proteins / analysis
Substances
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APOD protein, human
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Actins
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Apolipoproteins
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Apolipoproteins D
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Carrier Proteins
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Glycoproteins
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Membrane Glycoproteins
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Membrane Transport Proteins
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Mucin-1
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Neoplasm Proteins