Alpha-1-antitrypsin in islet cell tumors of the pancreas

Am J Clin Pathol. 1983 Sep;80(3):277-82. doi: 10.1093/ajcp/80.3.277.

Abstract

The presence of alpha-1-antitrypsin (A1AT) in normal pancreatic islets recently has been demonstrated, and serum elevation of A1AT in patients having pancreatic tumors has been reported. In the present study, the presence of A1AT in 12 of 33 islet cell tumors was demonstrated. The possible utility of A1AT as a marker for islet cell tumors is suggested.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenoma, Islet Cell / analysis*
  • Adenoma, Islet Cell / pathology
  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Inclusion Bodies / analysis
  • Male
  • Middle Aged
  • Pancreatic Neoplasms / analysis*
  • Pancreatic Neoplasms / pathology
  • alpha 1-Antitrypsin / analysis*

Substances

  • alpha 1-Antitrypsin