Abstract
We report two unique cases of metaplastic ossification occurring within a tubulovillous adenoma and a juvenile polyp. In both lesions, well-formed bony spicules were present that were adjacent to living epithelial cells. The metaplastic bone revealed vimentin positivity and cytokeratin negativity. The pathogenesis of osseous metaplasia in colorectal tumors remains unclear, but the process seems to have no clinical significance.
MeSH terms
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Adenoma, Villous / complications*
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Adenoma, Villous / pathology
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Aged
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Child, Preschool
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Colonic Polyps / complications*
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Colonic Polyps / pathology
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Female
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Humans
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Intestinal Neoplasms / complications*
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Intestinal Neoplasms / pathology
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Intestinal Polyps / complications*
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Intestinal Polyps / pathology
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Male
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Metaplasia
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Ossification, Heterotopic / etiology*
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Ossification, Heterotopic / pathology
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Rectal Diseases / complications*
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Rectal Diseases / pathology