RT Journal Article
SR Electronic
T1 Urinary beta-aminoisobutyric acid excretion in thalassaemia
JF Journal of Clinical Pathology
JO J Clin Pathol
FD BMJ Publishing Group Ltd and Association of Clinical Pathologists
SP 154
OP 157
DO 10.1136/jcp.22.2.154
VO 22
IS 2
A1 Ph. Fessas
A1 A. Koniavitis
A1 P. M. Zeis
YR 1969
UL http://jcp.bmj.com/content/22/2/154.abstract
AB The quantity of beta-aminoisobutyric acid (BAIB) excreted in the urine of patients with an intact spleen suffering from thalassaemia major appears to be proportional to the number of the circulating normoblasts and inversely proportional to the haemoglobin level. After splenectomy only minute amounts of BAIB are excreted. Transfusion constantly, but temporarily, reduces urinary excretion of beta-aminoisobutyric acid. Other anaemic but non-thalassaemic patients may excrete low levels.