PT  - JOURNAL ARTICLE
AU  - D Sawhney
AU  - S Hinder
AU  - D Swaine
AU  - E Y Bridson
TI  - Novel method for detecting micro-organisms in blood cultures.
AID  - 10.1136/jcp.39.11.1259
DP  - 1986 Nov 01
TA  - Journal of Clinical Pathology
PG  - 1259--1263
VI  - 39
IP  - 11
4099  - http://jcp.bmj.com/content/39/11/1259.short
4100  - http://jcp.bmj.com/content/39/11/1259.full
SO  - J Clin Pathol1986 Nov 01; 39
AB  - A method for detecting the growth of micro-organisms in blood culture by a visual signal is described. The system utilises a single blood culture medium that has been specifically formulated to support growth of aerobic, anaerobic, and microaerophilic micro-organisms. The system is based on the principle that when micro-organisms grow in the medium in a sealed bottle their metabolic products create positive pressure. This positive pressure displaces the infected blood and broth into an upper chamber, which acts as a visual signal of microbial activity. All the test micro-organisms, when inoculated at less than 20 colony forming units into simulated human blood cultures, gave a positive signal.