RT Journal Article SR Electronic T1 Novel method for detecting micro-organisms in blood cultures. JF Journal of Clinical Pathology JO J Clin Pathol FD BMJ Publishing Group Ltd and Association of Clinical Pathologists SP 1259 OP 1263 DO 10.1136/jcp.39.11.1259 VO 39 IS 11 A1 D Sawhney A1 S Hinder A1 D Swaine A1 E Y Bridson YR 1986 UL http://jcp.bmj.com/content/39/11/1259.abstract AB A method for detecting the growth of micro-organisms in blood culture by a visual signal is described. The system utilises a single blood culture medium that has been specifically formulated to support growth of aerobic, anaerobic, and microaerophilic micro-organisms. The system is based on the principle that when micro-organisms grow in the medium in a sealed bottle their metabolic products create positive pressure. This positive pressure displaces the infected blood and broth into an upper chamber, which acts as a visual signal of microbial activity. All the test micro-organisms, when inoculated at less than 20 colony forming units into simulated human blood cultures, gave a positive signal.