Table 1

Clinical situations in which Whipple's disease should be part of the differential diagnosis

Unexplained malabsorption on a background of systemic disease
Unexplained systemic granulomatous disease resembling sarcoidosis
Neurological disease characterised by myoclonus, dementia, and supranuclear ophthalmoplegia
Unexplained culture negative endocarditis
Unexplained uveitis