Histopathology results, excluding false negative interval cancers
| Screen detected | Symptomatic | Interval | False neg | Significance | ||
|---|---|---|---|---|---|---|
| Values are n (%) or median (range). | ||||||
| *Invasive cancers only; †malignant phyllodes tumour; ‡Nottingham prognostic index. | ||||||
| Calc, calculated; neg, negative. | ||||||
| Age (years) | 59 (48 to 66) | 57 (49 to 67) | 57 (35 to 72) | 59 (52 to 70) | ||
| In situ | 27 (24%) | 5 (4%) | 3 (4%) | 0 | ||
| Invasive | 85 (76%) | 107 (96%) | 82 (96%) | 27 (100%) | p<0.0001 | |
| Median size (mm)* | 14.8 | 22.4 | 19.5 | 22.0 | p<0.0001 | |
| Grade* | 1 | 38 (45%) | 11 (10%) | 19 (23%) | 2 (7%) | |
| 2 | 33 (39%) | 51 (48%) | 20 (25%) | 9 (33%) | ||
| 3 | 14 (16%) | 45 (42%) | 42 (51%) | 15 (56%) | ||
| Ungraded† | 0 | 0 | 1 (1%) | 1 (4%) | p<0.0001 | |
| Vascular invasion* | Absent | 73 (86%) | 61 (57%) | 54 (66%) | 14 (52%) | |
| Present | 12 (14%) | 46(43%) | 28 (34%) | 13 (48%) | p<0.0001 | |
| Number of positive lymph nodes* | 0 | 50 (59%) | 32 (30%) | 44 (54%) | 11 (41%) | |
| 1-3 | 14 (16%) | 28 (26%) | 18 (22%) | 8 (30%) | ||
| >3 | 7 (8%) | 22 (21%) | 8 (10%) | 3 (11%) | ||
| Not sampled | 14 (16%) | 25 (23%) | 12 (15%) | 5 (18%) | p=0.009 | |
| NPI*‡ | Good | 39 (46%) | 11 (10%) | 20 (24%) | 3 (11%) | |
| Moderate | 25 (29%) | 43 (40%) | 36 (44%) | 13 (48%) | ||
| Poor | 7 (8%) | 28 (26%) | 14 (17%) | 6 (22%) | ||
| Not calc | 14 (17%) | 25 (24%) | 12 (15%) | 5 (19%) | p<0.0001 | |