Effect of treatment on test result over nine months in a cohort of 15 patients
| Months | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient (sex) | Test | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | Comments |
| Aur, auramine staining; c, contaminated culture; Cul, culture for Mycobacterium tuberculosis; HIV, human immunodeficiency virus; INH, isonicotinic acid hyrazide; IVDU, intravenous drug user; TB, tuberculosis. | |||||||||||
| MA (male) | LCx | − − − − | − | − − + + + − | + + | Alcoholic liver disease, pulmonary TB, 12 months treatment, non-adherent, clinical resolution slow | |||||
| Aur | − − − − | − | − − − − − − | + + | |||||||
| Cul | − + − − | + | − − − − − − | + + | |||||||
| SB (male) | LCx | + + + + | − | − | Alcoholic, pulmonary TB non-adherent to treatment, at 7 months erratic treatment but tests negative | ||||||
| Aur | + + + + | − | − | ||||||||
| Cul | c + + + | − | − | ||||||||
| JC (male) | LCx | + + | + + + + | + | Pulmonary TB. Uncomplicated treatment course, lasting 6 months, fully compliant | ||||||
| Aur | + + | + + + + | + | ||||||||
| Cul | + + | + + + + | + | ||||||||
| SF (male) | LCx | + | + | + | HIV+, pulmonary TB, failed supervised treatment, continues on regimen of 1st and 2nd line anti-TB drugs in combination | ||||||
| Aur | + | + | − | ||||||||
| Cul | + | + | + | ||||||||
| AH (male) | LCx | − − − − − | − − − | + | Reactivated pulmonary TB, psoas abscess with B pseudomallei. Non-adherent, slow resolution | ||||||
| Aur | − − − − − | − − − | − | ||||||||
| Cul | − − − − − | − + c | − | ||||||||
| HJ (female) | LCx | − + − | − | Pulmonary TB, non-adherent, poor tolerance to anti-TB drugs, 9 months' treatment, slow resolution | |||||||
| Aur | − − − | − | |||||||||
| Cul | + + + | + | |||||||||
| MK (female) | LCx | − − | + − − | − | Miliary TB and cerebral cryptococcosis, refused HIV test. 6 months' treatment, TB resolved | ||||||
| Aur | − − | − − − | − | ||||||||
| Cul | − − | + + − | + | ||||||||
| JK (male) | LCx | − | − − | − − − | − | − − | HIV+, strain resistant to INH, on quadruple treatment >1 year, no resolution | ||||
| Aur | − | + − | − − − | − | − − | ||||||
| Cul | + | + + | − − + | − | − − | ||||||
| DL (male) | LCx | − − | + + | HIV+, Kaposi's sarcoma on chemotherapy, reactivated pulmonary TB 9 months' treatment resolved | |||||||
| Aur | − − | + + | |||||||||
| Cul | − − | + + | |||||||||
| MM (male) | LCx | − | − | + + − | Post renal transplant, pulmonary and metacarpal joint TB, 9 months' treatment resolved | ||||||
| Aur | − | − | − − − | ||||||||
| Cul | − | − | + + − | ||||||||
| JM (male) | LCx | + + + | + | Alcoholic, non-adherent, needed supervised treatment, 9 months course for pulmonary TB | |||||||
| Aur | + + + | − | |||||||||
| Cul | + + + | + | |||||||||
| AP (male) | LCx | + + − | − − − | Alcoholic myopathy, previous pulmonary TB, reactivation, completed 8 months course of treatment. | |||||||
| Aur | − − − | − − − | |||||||||
| Cul | − − − | − − − | |||||||||
| KR (male) | LCx | − + + | + + + | + + + | Miliary TB, cavitating lung lesions, hepatitis, poor tolerance to anti-TB drugs, slow resolution | ||||||
| Aur | − − − | − − − | − − − | ||||||||
| Cul | − − c | − − − | − − − | ||||||||
| FS (male) | LCx | + + + | − − − | IVDU, presented with lung abscess positive for TB, 9 months of treatment, adherent, slow to resolve | |||||||
| Aur | + − − | − − − | |||||||||
| Cul | + + − | − − − | |||||||||
| AW (male) | LCx | + | + + + | + + + | HIV+, pulmonary TB, non-adherent after 3 months' treatment, progressive disease. Died | ||||||
| Aur | + | − − − | − − − | ||||||||
| Cul | + | + − − | − − − | ||||||||
| WZ (male) | LCx | − | + + + | − | Homeless, pulmonary TB, non-adherent to treatment for 2 months, re-housed, supervised 6 months' treatment | ||||||
| Aur | − | − − − | − | ||||||||
| Cul | − | + − − | − | ||||||||