ALK expression in anaplastic large cell lymphoma (ALCL) according to site of origin
| Pattern of staining | |||||
|---|---|---|---|---|---|
| N | ALK expression | c/n | c | n | |
| ALK expression was determined by immunohistochemistry using the monoclonal antibodies ALK1 and ALKc. | |||||
| c/n, cytoplasmic and nuclear staining; c, cytoplasmic staining only; n, nuclear staining only; LPD, lymphoproliferative diseases. | |||||
| Systemic (nodal) ALCL | 51 | 20 | 15 | 5 | 0 |
| Primary gastrointestinal ALCL | 14 | 0 | – | – | – |
| Primary nasal ALCL | 5 | 0 | – | – | – |
| Cutaneous CD30+ LPD | |||||
| Primary cutaneous ALCL | 15 | 0 | – | – | – |
| Lymphomatoid papulosis | 7 | 0 | – | – | – |