Patient characteristics, histopathology (Sydney) scores, and cytokine secretion (“control” biopsies)
| Helicobacter pylori +ve | Helicobacter pylori −ve | |
|---|---|---|
| Values for cytokine secretion are median (interquartile range), expressed as pg/mg/24 hours. | ||
| *p < 0.05 for H pylori +ve v H pylori −ve (Mann Whitney U test). | ||
| TNF-α, tumour necrosis factor α. | ||
| Number | 31 | 10 |
| Mean age (range) | 57.9 (32–84) | 57.4 (23–87) |
| Male/female ratio | 18/13 | 5/5 |
| Antral inflammation | ||
| Absent or mild (0, 1) | 12/31 | 10/10 |
| Moderate or severe (2, 3) | 19/31 | 0/10 |
| Antral activity | ||
| Absent or mild (0, 1) | 20/31 | 10/10 |
| Moderate or severe (2, 3) | 11/31 | 0/10 |
| Cytokine secretion | ||
| TNF-α | 0.72* (0.27–1.20) | 0.00 (0.00–0.18) |
| Interleukin 6 | 27.30* (14.30–67.30) | 10.50 (5.65–12.72) |
| Interleukin 8 | 1122* (684–1864) | 324 (269.5–533.7) |