AP-2α, AP-2β, and AP-2γ protein and AP-2α mRNA expression and histological features of the carcinomas
| Case | Dukes's grade | Histological grade | AP-2α protein expression | AP-2β protein expression | AP-2γ protein expression | AP-2α mRNA expression |
|---|---|---|---|---|---|---|
| *Corresponding mRNA and protein positive and negative areas; ‡AP-2α positivity in <5% of nuclei. | ||||||
| The percentages presented describe cytoplasmic staining in tumour cells.mRNA expression: –, negative; +, focally positive; ++, diffusely positive, moderate; +++, diffusely positive, strong. | ||||||
| 1 | B | 2 | 10% | 20% | 5% | ++ |
| 2 | D | 3 | 0% | 50% | 10% | ++ |
| 3 | C | 2 | 0% | 60% | 20% | +++ |
| 4 | D | 2 | 10% | 35% | 5% | +++‡ |
| 5 | D | 2 | 0% | 10% | 10% | + |
| 6 | C | 2 | 0% | 35% | 10% | ++ |
| 7 | D | 2 | 0% | 10% | 10% | + |
| 8 | C | 3 | 0% | 60% | 5% | ++ |
| 9 | C | 1 | 5% | 70% | 20% | ++ |
| 10 | C | 3 | 0% | 10% | 0% | ++ |
| 11 | B | 2 | 10% | 70% | 20% | +* |
| 12 | A | 2 | 80% | 100% | 20% | + |
| 13 | B | 2 | 20% | 70% | 60% | ++* |
| 14 | B | 3 | 30% | 30% | 20% | ++*‡ |
| 15 | A | 2 | 80% | 45% | 5% | ++ |
| 16 | C | 2 | 70% | 70% | 60% | + |
| 17 | A | 2 | 0% | 20% | 15% | + |
| 18 | C | 2 | 30% | 40% | 5% | +++ |
| 19 | C | 1 | 20% | 60% | 40% | +* |
| 20 | B | 2 | 90% | 15% | 10% | ++*‡ |
| 21 | D | 2 | 0% | 35% | 5% | –* |
| 22 | B | 1 | 5% | 10% | 30% | +*‡ |
| 23 | A | 1 | 80% | 80% | 80% | + |
| 24 | C | 1 | 10% | 80% | 70% | +* |
| 25 | D | 1 | 0% | 40% | 10% | ++ |
| 26 | C | 3 | 0% | 0% | 0% | ++ |
| 27 | B | 2 | 20% | 80% | 30% | + |
| 28 | C | 1 | 60% | 80% | 80% | +++* |
| 29 | B | 1 | 30% | 80% | 30% | ++* |
| 30 | B | 2 | 0% | 5% | 5% | + |