Frequency of α1 antitrypsin phenotypes in healthy Chinese adults
| Type/subtypes | Variants | Number | Frequency (f) |
|---|---|---|---|
| Homozygous M | M1 M1 | 649 | 0.598 |
| n = 717, f = 0.661 | M2 M2 | 68 | 0.063 |
| M3 M3 | 0 | 0.000 | |
| M4 M4 | 0 | 0.000 | |
| Heterozygous M | M1 M2 | 312 | 0.288 |
| n = 353, f = 0.326 | M1 M3 | 11 | 0.010 |
| M2 M3 | 30 | 0.028 | |
| Other heterozygous | M1 S | 3 | 0.003 |
| n = 15, f = 0.015 | M2 S | 1 | 0.001 |
| M1 E | 4 | 0.004 | |
| M1P | 4 | 0.004 | |
| M1L | 2 | 0.002 | |
| M2 N | 1 | 0.001 | |
| Total | 1085 | 1.000 |