In vitro expansion of 20% of an umbilical cord blood donation
| CD34+ | CFU-GM | LTC-IC | |
|---|---|---|---|
| *One unit represents 20% cell content of one umbilical cord blood donation. | |||
| **Unit equivalent allowing for cell losses during processing. | |||
| †0.8 represents 0.8 units or 80% of an umbilical cord blood unit infused without in vitro expansion. | |||
| CFU-GM, granulocyte–macrophage colony forming units; LTC-IC longterm culture initiating cells. | |||
| Fraction used for expansion | 0.2 unit* | 0.2 unit | 0.2 unit |
| Post processing fraction | 0.15 unit** | 0.15 unit | 0.15 unit |
| Fold expansion | ×43 | ×50 | ×3 |
| Post expansion equivalent | 6.5 units | 7.5 units | 0.45 units |
| Total yield (unit equivalent) | 6.5 + 0.8† = 7.3 | 7.5 + 0.8 = 8.3 | 0.45 + 0.8 = 1.25 |