Features of Helicobacter pylori isolates and patients with sera giving negative or borderline results in the CagA ELISA assay
| Strain | Strain genotype | Patient age (years) | Clinical details |
|---|---|---|---|
| Strain genotype: cagA*, strain gave negative result with F1/B1 primer pair but was positive with the F008/R008 primer pair; ES+*, non-specific product amplified as well as predicted amplicon; ES−*, only non-specific product amplified. | |||
| DU, duodenal ulcer; ELISA, enzyme linked immunosorbent assay; GU, gastric ulcer. | |||
| CagA− ELISA | |||
| H292 | cagA*/s1m1/ES+* | 35 | DU |
| H293 | cagA*/s1m2/ES+ | 55 | Mild oesophagitis |
| H115 | cagA*/s1m2/ES−* | 56 | GU |
| H377 | cagA*/s1m2/ES−* | 75 | GU/DU |
| H298 | cagA/s1m2/ES−* | 67 | DU |
| Borderline CagA ELISA | |||
| H6 | cagA/s1m2/ES−* | 37 | DU |
| H339 | cagA*/s1m1/ES−* | 68 | Gastric neoplasia |