Expression of cytotoxic proteins and EBV status of neoplastic cells in nodal and extranodal lymphomas
| Diagnosis | N | GrB/TIA-1 | EBV | CD3 | CD4 | CD8 | CD56 |
|---|---|---|---|---|---|---|---|
| *Only two cases tested. | |||||||
| ALCL, anaplastic large cell lymphoma; EBV, Epstein-Barr virus; GrB, granzyme B; LTCL, large T cell lymphoma; NK, natural killer; NOS, not otherwise specified. | |||||||
| True NK cell lymphomas | |||||||
| Nasal | 4 | 4/4 | 4/4 | 0/4 | 0/4 | 0/4 | 4/4 |
| Cutaneous | 4 | 4/4 | 0/4 | 0/4 | 4/4 | 0/4 | 4/4 |
| Intestinal lymphoma, nasal type | 1 | 1/1 | 0/1 | 0/1 | 0/1 | 0/1 | 1/1 |
| T cell lymphomas with a cytotoxic phenotype | |||||||
| Enteropathy-type T cell lymphoma | 5 | 5/5 | 0/2* | 5/5 | 0/5 | 3/5 | 0/5 |
| Nodal CD30+ ALCL | 5 | 5/5 | 0/5 | 5/5 | 5/5 | 0/5 | 0/5 |
| CD30+ cutaneous LTCL | 5 | 3/5 | 0/5 | 5/5 | 5/5 | 0/5 | 0/5 |
| Lymphomatoid papulosis | 8 | 8/8 | 0/8 | 8/8 | 8/8 | 0/8 | 0/8 |
| Mycosis fungoides | 6 | 6/6 | 0/6 | 6/6 | 5/6 | 1/6 | 0/6 |
| T cell lymphomas without a cytotoxic phenotype | |||||||
| Mycosis fungoides | 12 | 0/12 | 0/12 | 12/12 | 12/12 | 0/12 | 0/12 |
| CD30− cutaneous LTCL | 2 | 0/2 | 0/2 | 2/2 | 2/2 | 0/2 | 0/2 |
| Nodal T cell lymphoma NOS | 5 | 0/5 | 0/5 | 5/5 | 5/5 | 0/5 | 0/5 |