Patient | MSI status | Germline mutation | MLH1 expression | MSH2 expression |
---|---|---|---|---|
*MLH1 exon 6, codon 175, 10 bp deletion; †MLH1 exon 19, codon 753, T deletion; ‡MLH1 exon 13, codon (CGA to TGA ) 487 stop; ¶MLH1 exon 17, codon 646, AG insertion. | ||||
MMR, DNA mismatch repair; MSI, microsatellite instability. | ||||
2142 | + | +* | – | + |
4046 | + | – | – | + |
2140 | + | – | + | – |
4020 | + | – | + | – |
4002 | + | – | – | + |
2055 | + | – | – | + |
2112 | + | – | – | + |
2217 | + | – | + | + |
4088 | + | +† | – | + |
2181 | + | – | – | + |
2047 | + | – | – | + |
2088 | + | – | – | + |
2065 | + | – | – | + |
2185 | + | – | + | – |
2204 | + | +‡ | – | + |
2137 | + | – | + | – |
140 | + | – | – | + |
2183 | + | – | – | + |
331 | + | +¶ | – | + |
4094 | + | – | + | – |
82 | + | – | – | + |
70 | + | – | – | + |
4171 | + | – | – | + |
2020 | – | + | + | |
2045 | – | + | + | |
2090 | – | + | + | |
2196 | – | + | + | |
2127 | – | + | + | |
2109 | – | + | + | |
2154 | – | + | + | |
409 | – | + | + | |
386 | – | + | + | |
382 | – | + | + | |
337 | – | + | + | |
88 | – | + | + | |
2174 | – | + | + | |
2205 | – | + | + | |
4053 | – | + | + | |
2193 | – | + | + | |
2209 | – | + | + | |
2091 | – | + | + | |
2015 | – | + | + | |
2037 | – | + | + | |
2085 | – | + | + | |
2084 | – | + | + | |
2201 | – | + | + |