Patient characteristics
| Age less than 56 years | Age 56 years and above | |
|---|---|---|
| *Patients over 55 years treated with curative intent. | ||
| CI, confidence interval; CR, complete remission; Hb, haemoglobin; MRC, Medical Research Council; WBC, white blood cell count. | ||
| Number | 12 (8 male, 4 female) | 21 (13 male, 8 female) |
| Median age (range) | 39 years (3–53) | 69 years (57–84) |
| Median Hb (range) | 84 g/l (49–105) | 74 g/l (31–114) |
| Median WBC (range) | 6.8 × 109/l (0.7–32.3) | 5.9 × 109/l (1.1–36.1) |
| Karyotype (classified by MRC criteria) | 6 standard risk | 9 standard risk |
| 4 poor risk | 8 poor risk | |
| 2 not done | 4 not done | |
| No. treated with curative intent | 12 | 10 |
| CR rate (95% CI) | 58% (28% to 85%) | 40% (12% to 74%)* |
| Median overall survival (range) | 11 months (0–191) | 3 months (0–180)* |
| Median event free survival (range) | 4.5 months (0–120) | 0 months (0–180)* |
| Overall 5 year survival (95% CI) | 8% (0.2% to 15.8%) | 5% (0.2% to 45%)* |