Acquired |
Liver disease |
Vitamin K deficiency |
Severe renal failure |
Hypothyroidism |
Disseminated intravascular coagulation from any cause |
Diseases of bone marrow |
Myeloma |
Myeloproliferative disorders |
Myelodysplasia |
Use of antithrombotic medications |
Heparin |
Warfarin |
Aspirin |
Non-steroidal anti-inflammatory drugs |
Thrombocytopenia |
In bone marrow failure |
Autoimmune |
In hypersplenism |
In human immunodeficiency virus infection |
In massive transfusion |
As a result of haemolytic uraemic syndrome |
As a result of thrombotic thrombocytopenic purpura |
Congenital |
Von Willebrand's disease |
Haemophilia |